FDA溶出度方法库(AI中文)2730条
药品名称
剂型
USP溶出方法
转速（转/min）
溶出介质
容积
荐采样时间
更新时间
Loperamide HCl
Oral Suspension
II (Paddle)
25
0.01 N HCl
900
10, 20, 30, 45, 60, 75 and 90
06/25/2015
Loperamide HCl
Tablet
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Loperamide HCl
Capsule
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Lomustine
Capsule
Develop a dissolution method
12/24/2015
Lomitapide Mesylate
Capsule
II (Paddle)
50
0.001 N HCl with 0.1% Polysorbate 80
5, 10, 20, 30 and 45
06/25/2015
Lomefloxacin HCl
Tablet
II (Paddle)
50
0.01 N HCl
900
10, 20, 30 and 45
02/05/2004
Lithium Carbonate
Tablet (Extended Release)
Refer to USP
01/14/2008
Lithium Carbonate
Tablet
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Lithium Carbonate
Capsule
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Lisinopril
Tablet
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Lisdexamfetamine Dimesylate
Capsule
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Liothyronine Sodium
Tablet
Refer to USP
06/18/2007
Linezolid
Tablet
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Linezolid
Suspension
II (Paddle)
50
0.05 M Phosphate Buffer, pH 6.8
900
10, 20, 30 and 45
01/14/2008
Linagliptin/Metformin HCl
Tablet (Extended Release)
I (Basket)
100
Simulated Gastric Fluid (SGF) without enzyme (pH 1.2) (degassed)
900
Linagliptin 10, 15, 20, 30 and 45 minutes; Metformin: 1, 2, 4, 6, 8 and 12 hours
07/28/2016
Linagliptin/Metformin HCl
Tablet
II (Paddle)
50
0.1 N HCl
5, 10, 15, 20, 30 and 45
05/15/2014
Linagliptin
Tablet
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Linaclotide
Capsule
I (Basket)
50
50 mM Phosphate Buffer, pH 4.5
500
5, 10, 15, 20 and 30
12/24/2015
Lidocaine
Topical Patch
Paddle over Disk (Apparatus 5)
50
Acetic acid/sodium acetate buffer, pH 4.0 at 32ºC
500
10, 20, 30, 60, 120 and 180
01/03/2007
Levothyroxine Sodium
Tablet
Refer to USP
07/25/2007