FDA溶出度方法库(AI中文)2730条
药品名称
剂型
USP溶出方法
转速（转/min）
溶出介质
容积
荐采样时间
更新时间
Nystatin
Oral Suspension
II (Paddle)
0.1 % and 0.2% SLS in water
900
5, 10, 20, 30, 45 and 60
10/28/2010
Nystatin
Tablet
II (Paddle)
75
Water with 0.1% SLS
900
15, 30, 45, 60 and 90
01/03/2007
Nortriptyline HCl
Capsule
Refer to USP
09/03/2015
Norethindrone Acetate
Tablet
Refer to USP
08/27/2009
Norethindrone
Tablet
Refer to USP
10/08/2009
Nizatidine
Capsule
Refer to USP
01/14/2008
Nitroglycerin
Film, Transdermal (Extended Release)
Modified USP Type V (Paddle-over-disk)
100
Deionized Water at 32º C
900
10, 20, 30, 45, 60, 90, 120 and 180
04/08/2010
Nitroglycerin
Tablet (Sublingual)
II (Paddle)
50
Phosphate Buffer, pH 6.5
500
1, 3, 5, 8, and 10
01/15/2010
Nitrofurantoin
Suspension
II (Paddle)
50
Phosphate Buffer, pH 7.2
900
15, 30, 60, 120 and 180
04/02/2009
Nitrofurantoin
Capsule
Refer to USP
04/02/2009
Nitisinone
Capsule
II (Paddle) with sinker
50
Phosphate Buffer, pH 6.8
1000
5, 10, 15, 20, 30 and 45
11/02/2017
Nitisinone
Suspension
II (Paddle)
50
pH 1.2 HCl Buffer (degassed)
1000
10, 15, 20, 30 and 45
12/22/2016
Nitisinone
Tablet
II (Paddle)
50
Phosphate Buffer, pH 6.8
10, 15, 20, 30, 45, 60, 75 and 90
02/15/2018
Nitazoxanide
Oral Suspension
II (Paddle
100
Phosphate buffer at pH 7.5 with 6% hexadecyltrimethyl ammonium bromide, bath temperature at 25ºC
900
10, 20, 30, 45 and 60
10/21/2010
Nitazoxanide
Tablet
II (Paddle)
75
Phosphate buffer at pH 7.5 with 6% hexadecyltrimethyl ammonium bromide, bath temperature at 25ºC
900
10, 20, 30, 45, 60
01/03/2007
Nisoldipine
Tablet (Extended Release)
II (Paddle) with option to use a sinker
50
HCl with SLS (32.5 ± 0.1 g Sodium Lauryl Sulfate in 6489 mL of purified water containing 17.0 mL HCl, pH adjusted to 1.20 ± 0.05 with HCl)
900
1, 4, 8, 12, 15, 18 and 24 hours
04/02/2009
Niraparib
Capsule
II (Paddle) with sinker
50
Tier 1: 0.08M Sodium Acetate Buffer, pH 4.0; Tier 2: 0.08M Sodium Acetate Buffer, pH 4.0 containing pepsin (750,000 units/L)
900
10, 15, 20, 30, 45 and 60
11/02/2017
Nintedanib Esylate
Capsule
II (Paddle) with sinker
100
0.1 N HCl
900
10, 15, 20, 30, 45 and 60
09/03/2015
Nimodipine
Capsule
II (Paddle)
50
0.5% SDS in water
900
10, 20, 30, and 45
04/09/2007
Nilutamide
Tablet
Develop a dissolution method
05/20/2009