FDA溶出度方法库(AI中文)2730条
药品名称
剂型
USP溶出方法
转速（转/min）
溶出介质
容积
荐采样时间
更新时间
Paroxetine Mesylate
Capsule
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Paroxetine HCl
Suspension
II (Paddle)
100
SGF without enzyme
900
10, 20, 30 and 45
02/13/2004
Paroxetine HCl
Tablet
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Paroxetine
Tablet (Extended Release)
Refer to USP
11/19/2015
Paromomycin Sulfate
Capsule
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Paricalcitol
Capsule
I (Basket)
100
4 mg/mL (0.4%) Lauryldimethylamine N-oxide (LDAO)
500
20, 30, 45, 60
06/18/2007
Pantoprazole Sodium
Delayed Release Granules for Oral Suspension
II (Paddle)
100
Acid Stage: 0.1 N Hydrochloric Acid; Buffer Stage: 0.05 M Tribasic Sodium Phosphate (Add 250 mL of 0.2 mM Tribasic Sodium Phosphate after completion of acid stage); pH 6.8 (Method B)
Acid stage: 60, 90 and 120; Buffer stage: 10, 20, 30, 45 and 60
10/30/2009
Pantoprazole Sodium
Tablet (Delayed Release)
Refer to USP
07/21/2009
Panobinostat Lactate
Capsule
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Pancrelipase
Tablet
II (Paddle)
50
Phosphate Buffer, pH 4.5
900
10, 20, 30, 45 and 60
06/02/2016
Pancrelipase
Capsule (Delayed Release)
Refer to USP
03/17/2016
Palonosetron HCl
Capsule
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Paliperidone Palmitate [3-month injection]
Intramuscular Suspension (Extended Release)
II (Paddle)
50
0.489% (w/v) Polysorbate 20 in 0.001 N HCl @25.0 °C.
900
5, 30, 60, 90, 120, 180, 240, 300 and 360
03/17/2016
Paliperidone Palmitate
Intramuscular Suspension (Extended Release)
II (Paddle)
50
0.489% (w/v) Polysorbate 20 in 0.001 N HCl @25.0 °C.
900
1.5, 5, 8, 10, 15, 20, 30 and 45
09/01/2011
Paliperidone
Tablet (Extended Release)
II (Paddle)
50
Modified SGF, pH 1.0 [NaCl (0.2% w/w) in 0.0825N HCl]
500
1, 2, 4, 6, 8, 12, 14, 18 and 24 hours
08/27/2009
Palbociclib
Capsule
II (Paddle) with sinker
50
0.1 N HCl
900
10, 15, 20, 30 and 45
03/17/2016
Oxymorphone HCl
Tablet (Extended Release)
II (Paddle) with sinker
50
45 mM Phosphate Buffer, pH 4.5
900
1, 2, 4, 6, 8 and 10 hours
02/14/2014
Oxymorphone HCl
Tablets
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Oxycodone HCl/ Naloxone HCl
Tablet (Extended Release)
II (Paddle)
50
Simulated Gastric Fluid [SGF, pH 1.2] without enzyme
900
0.25, 0.5, 1, 2, 4, 6, 8, 10 and 12 hours
12/22/2016
Oxycodone HCl
Tablet (Extended Release)
Refer to USP
03/17/2016