FDA溶出度方法库(AI中文)2730条
药品名称
剂型
USP溶出方法
转速（转/min）
溶出介质
容积
荐采样时间
更新时间
Nilotinib Hydrochloride Monohydrate
Capsule
I (Basket)
100
0.1 N HCl
1000
10, 15, 30 and 45
10/30/2009
Nifedipine
Tablet (Extended Release)
Refer to USP
07/25/2007
Nifedipine
Capsule
Refer to USP
03/03/2011
Nicotine Polacrilex
Lozenge (Mini)
III (Reciprocating Cylinder)
Phosphate buffer pH 7.4
250
15, 30, 45, 60 and 90
03/09/2017
Nicotine Polacrilex
Lozenge
I (Basket)
100
Phosphate Buffer, pH 7.4
900
0.5, 1, 2, 3, 6 and 8 hours
12/23/2010
Nicotine Polacrilex
Chewing Gum
Chewing Machine as desribed in European Pharmacopoeia (2.9.25)
Phosphate Buffer, pH 7.4 or or any other appropriate buffer and conditions
20
5, 10, 20 and 30
01/05/2012
Nicotine
Film, Transdermal (Extended Release)
Refer to USP
01/31/2013
Nicardipine HCl
Capsule
II (Paddle)
50
0.033 M Citric Acid Buffer, pH 4.5
900
10, 20, 30 and 45
02/11/2004
Nicardipine HCl
Capsule (Extended Release)
II (Paddle)
50
0.1 N HCl
1000
0.5 , 2 and 6 hours
07/14/2008
Niacin/Simvastatin
Tablet (Extended Release)
Niacin: I (40 mesh rotating Basket); Simvastain: I (10 mesh rotating Basket)
100
Niacin: Water; Simvastatin: 0.5 % SDS in 0.01 M Sodium Phosphate, pH 7.0
900
Niacin: 1, 3, 6, 9, 12, 15, 18, 20 and 24 hours; Simvastatin: 10, 20, 30, 45 and 60
01/15/2010
Niacin
Tablet (Extended Release)
I (Basket)
100
Water
900
1, 3, 6, 9, 12, 15, 20 and 24 hours
06/10/2009
Nevirapine
Tablet
Refer to USP
09/13/2007
Nevirapine
Suspension
II (Paddle)
25
0.1 N HCl
900
10, 20, 30, 45 and 60
02/11/2004
Nevirapine
Tablet (Extended Release)
I (Basket)
75
0.04 M Sodium phosphate buffer pH 6.8 containing 2% sodium lauryl sulfate
900
1, 2, 3, 4, 5, 6, 8, 10, 12, 16 and 20 hours
01/31/2013
Netupitant/Palonosetron HCl
Capsule
II (Paddle)
Netupitant: 0.07M Phosphate buffer pH 6.8 containing 1% sodium SDS ; Palonosetron: 0.01 N HCl
Netupitant: 10, 20, 30, 45, 60 and 75; Palonosetron: 5, 10, 15, 20, 30 and 45
09/03/2015
Nepafenac
Ophthalmic Suspension
Develop a method to characterize in vitro release
08/14/2014
Neomycin Sulfate
Tablet
II (Paddle)
50
0.05 M Phosphate Buffer, pH 6.8
900
15, 30, 45 and 60
01/14/2008
Nelfinavir Mesylate
Powder for Suspension
II (Paddle)
50
0.1 N HCl
900
5, 10, 15, 20, 30, and 45
09/13/2007
Nelfinavir Mesylate
Tablet
II (Paddle)
50
0.1 N HCl
900
5, 10, 15, 20, 30, 45, 60 and 90
01/03/2007
Nefazodone HCl
Tablet
II (Paddle)
50
0.1 N HCl
900
10, 20, 30, 45 and 60
01/03/2007