FDA溶出度方法库2730条
药品名称
剂型
USP溶出方法
转速（转/min）
溶出介质
容积
荐采样时间
更新时间
Etravirine (25 and 100 mg)
Tablet
II (Paddle)
50
1.0 % Sodium lauryl sulfate (SLS) in 0.01 M HCl in two phases: Phase 1: 500 mL of degassed 0.01 M HCl for 10 minutes. Phase 2: Add 400 mL of 2.25% SLS in 0.01 M HCl.
Phase 1: No Sampling. Phase 2: 5, 10, 20, 30, 45, 60 and 90
08/14/2014
Everolimus
Tablet
II (Paddle)
50
Water with 0.4% sodium dodecylsulfate
500
10, 20, 30 and 45
07/01/2010
Exemestane
Tablet
I (Basket)
100
0.5%(w/v) SLS Solution
900
10, 20, 30 and 45
08/17/2006
Ezetimibe
Tablet
II (Paddle)
50
0.45% SLS in 0.05 M Acetate Buffer, pH 4.5
500
10, 20, 30 and 45
01/14/2008
Ezetimibe/Simvastatin
Tablet
II (Paddle)
50
0.01 M Sodium Phosphate, pH 7.0/0.5% SDS
900
5, 10, 20 and 30
01/03/2007
Ezogabine
Tablet
II (Paddle)
75
0.01 N HCl
1000
5, 10, 15, 20 and 30
08/15/2013
Famciclovir
Tablet
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Famotidine
Tablet
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Famotidine
Tablet (Orally Disintegrating)
II (Paddle)
50
0.1 M Phosphate Buffer, pH 4.5
900
2, 5, 10, 15 and 20
10/06/2008
Famotidine
Tablet (Chewable)
II (Paddle)
50
0.1 M Phosphate Buffer, pH 4.5
900
10, 20, 30, 45 and 60
01/29/2004
Famotidine
Suspension
II (Paddle)
0.1 M Phosphate buffer, pH 4.5
900
10, 15, 30 and 45
11/25/2008
Famotidine/Calcium Carbonate/Magnesium Hydroxide
Tablet (Chewable)
Develop a dissolution method
12/15/2009
Famotidine/Ibuprofen
Tablet
II (Paddle)
50
0.05 M Phosphate Buffer, pH 7.2
900
5, 10, 15, 20, 30 and 45
08/15/2013
Febuxostat
Tablet
II (Paddle)
75
0.05 M Phosphate Buffer, pH 6.0
900
5, 10, 15, 20 and 30
08/15/2013
Felbamate
Tablet
Refer to USP
08/15/2013
Felbamate
Suspension
II (Paddle)
50
Water (deaerated)
900
5, 10, 15 and 30
01/28/2004
Felodipine
Tablet (Extended Release)
Refer to USP
01/14/2008
Fenofibrate
Capsule
II (Paddle)
75
Phosphate Buffer w/ 2% Tween 80 and 0.1% pancreatin, pH 6.8
900
15, 30, 45, 60, 90 and 120
02/19/2008
Fenofibrate
Capsule (Micronized)
II (Paddle)
75
0.025 M SLS in water
1000
10, 20, 30, 40 and 60
06/03/2008
Fenofibrate (40 mg and 120 mg)
Tablet
II (Paddle
75
0.75% Sodium lauryl sulfate in water
900
5, 10, 20, 30, 45 and 60
10/21/2010