FDA溶出度方法库2730条
药品名称
剂型
USP溶出方法
转速（转/min）
溶出介质
容积
荐采样时间
更新时间
Fenofibrate (48 mg and 145 mg)
Tablet
II (Paddle
50
25 mM Sodium lauryl sulfate in water
1000
5, 10, 20, 30, 45 and 60
10/21/2010
Fenofibrate (54 mg and 160 mg)
Tablet
II (Paddle
50
0.05 M Sodium lauryl sulfate in water
1000
5, 10, 20, 30, 45 and 60
10/21/2010
Fenofibric Acid
Tablet
II (Paddle)
75
Phosphate buffer, pH 6.8
900
5, 15, 30, 45 and 60
08/05/2010
Fenoprofen Calcium
Capsule
Refer to USP
11/25/2008
Fentanyl
Transdermal
VII (Reciprocating holder)- cylinder.
Equimolar mixture of 0.005 M phosphoric acid solution, and 0.005 M sodium phosphate, monobasic monohydrate (pH ~ 2.6). at 32° C. Change the test samples into fresh pre-equilibrated release medium at the time points indicated. Remove the protective liner and place the film onto a piece of nylon netting with adhesive facing the net. Secure the netting and transdermal system using nylon tie wraps at the top and bottom of the cylinder on the holder. The adhesive side faces towards the media.
0.5, 1, 2, 4 and 24 hours
06/09/2011
Fentanyl Citrate
Lozenges
II (Paddle)
175
0.1 M Phosphate Buffer, pH 4.5
500
5, 10, 20, 30 and 40
05/20/2009
Fentanyl Citrate
Tablet (Sublingual)
II (Paddle)
50
Phosphate Buffer, pH 6.8
500
1, 3, 5, 7, 10, 15 and 20
08/15/2013
Fentanyl Citrate (0.1 mg and 0.4 mg)
Tablet (Buccal)
II (Paddle) small volume dissolution apparatus
100
Phosphate Buffered Saline solution, pH 7.0
100
3, 5, 7.5, 10, 15 and 20
11/20/2009
Fentanyl Citrate (0.2 mg, 0.3 mg, 0.6 mg and 0.8 mg)
Tablet (Buccal)
II (Paddle) small volume dissolution apparatus
100
Phosphate Buffered Saline solution, pH 7.0
200
3, 5, 7.5, 10, 15 and 20
11/20/2009
Fentanyl Citrate (0.2 mg, 0.4 mg, 0.6 mg and 0.8 mg)
Film (Buccal)
I (Basket) 100 mL dissolution vessel
100
25-mM Phosphate Buffer, pH 6.4
60
5, 10, 15, 20, 30 and 45
12/15/2009
Fentanyl Citrate (1.2 mg)
Film (Buccal)
I (Basket) 100 mL dissolution vessel
100
25-mM Phosphate Buffer, pH 6.4
100
5, 10, 15, 20, 30 and 45
12/15/2009
Ferric Citrate
Tablet
II (Paddle)
100
EDTA media ( 2.0 grams of EDTA Na2 2H2O to 1000 mL of purified water)
900
10, 20, 30, 45 and 60
08/27/2015
Ferric Maltol
Capsule
II (Paddle with sinker)
75
Tier 1: KCl/HCl Buffer, pH 1.2; Tier 2: KCl/HCl Buffer pH 1.2, with pepsin
1000
5, 10, 20, 30 and 45
01/30/2020
Ferrous Fumarate
Tablet
Refer to USP
03/17/2016
Fesoterodine Fumarate
Tablet (Extended Release)
II (Paddle) with sinker
75
Phosphate Buffer, pH 6.8
900
1, 2, 4, 6, 8, 10, 12, 16 and 20 hours
08/15/2013
Fexofenadine HCl
Tablet
II (Paddle)
50
0.001 N HCl
900
5, 10, 20, 30 and 45
02/19/2004
Fexofenadine HCl
Capsule
II (Paddle)
50
Water (deaerated)
900
10, 20, 30, 45 and 60
01/29/2004
Fexofenadine HCl
Suspension
II (Paddle)
50
0.001 N HCl
900
10, 20, 30 and 45
11/25/2008
Fexofenadine HCl
Tablet (Orally Disintegrating)
II (Paddle)
50
0.001 N HCl
500
5, 10, 15, 30 and 45
09/03/2008
Fexofenadine HCl/Pseudoephedrine HCl
Tablet (Extended Release)
Refer to USP
04/02/2009