FDA溶出度方法库2730条
药品名称
剂型
USP溶出方法
转速（转/min）
溶出介质
容积
荐采样时间
更新时间
Anagrelide HCl
Capsule
I (Basket)
100
0.1 N HCl
900
5, 10, 15, 30 and 45
01/14/2004
Anastrozole
Tablet
Refer to FDA's Dissolution Guidance, 2018
07/02/2020
Apixaban
Tablet
II (Paddle)
75
0.05 M Sodium Phosphate Buffer with 0.05% SLS, pH 6.8
900
5, 10, 20, 30 and 45
05/09/2013
Apremilast
Tablet
II (Paddle)
60
0.15% SLS in 25 mM Sodium Phosphate Buffer, pH 6.8
900
10, 15, 20, 30, and 45
05/18/2017
Aprepitant
For Oral Suspension
II (Paddle)
50
Water (with 1.2% Tween 80)
900
5, 10, 15 and 20
03/17/2016
Aprepitant
Capsule
II (Paddle)
100
2.2% sodium dodecyl sulfate in distilled water
900
10, 15, 20, 30 and 45
01/20/2006
Aripiprazole
Tablet
Refer to USP
06/30/2016
Aripiprazole
Tablet (Orally Disintegrating)
II (Paddle)
75
Acetate Buffer, pH 4.0
1000
10, 20, 30 and 45
08/11/2008
Aripiprazole
For Intramuscular Suspension (Extended Release)
II (Paddle)
50
0.25% Sodium Dodecyl Sulfate (SDS) Solution
900
10, 15, 30, 60, 120, 180, 240, 300, 360, 420 and 480
06/25/2015
Armodafinil
Tablet
II (Paddle)
50
0.1 N HCl
900
10, 20, 30 and 45
01/14/2008
Asenapine
Transdermal
VI (Cylinder)
50
pH 5.1 Acetate Buffer at 32°C
900
1, 2, 3, 4, 6, 8, 10 and 12 hours
04/22/2021
Asenapine Maleate
Tablet (Sublingual)
II (Paddle)
50
Acetate Buffer, pH 4.5
500
1, 2, 3, 4 and 5
05/09/2013
Aspirin
Capsule
Refer to USP
05/28/2015
Aspirin
Capsule (Extended Release)
II (Paddle) with sinker
100
0.05M Potassium Phosphate Buffer (pH 7.4) with trypsin (.001%w/v) and sodium azide (.025% w/v)
900
1, 2, 3, 6, 9, 12, 16, 22 and 30 hours
10/20/2016
Aspirin/ Omeprazole
Tablet (Delayed Release)
I (Basket)
100
Acid Stage: 0.1 N HCl (degassed); Buffer Stage: Phosphate Buffer, pH 6.8 (degassed)
Acid Stage:120; Buffer Stage:10, 20, 30, 45, 60 and 75
12/22/2016
Aspirin/Butalbital/Caffeine
Capsule
Refer to USP
06/24/2010
Aspirin/Butalbital/Caffeine
Tablet
Refer to USP
06/24/2010
Aspirin/Butalbital/Caffeine/Codeine Phosphate
Capsule
Refer to USP
08/27/2009
Aspirin/Caffeine/Orphenadrine Citrate
Tablet
I (Basket)
75
Water (deaerated)
900
10, 20, 30, 45 and 60
01/15/2004
Aspirin/Dipyridamole
Capsule
I (Basket)
100
0.01 N HCl for first hour, 0.1 M Phosphate Buffer, pH 5.5, thereafter
Acid: 10, 20, 30, 45 and 60 min; Buffer:1, 2, 5, and 7 hours
10/09/2007